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Coagulation Case Studies


Wednesday, June 4, 2008

A sample is sent on a 4 month old baby

Two small blue tops are received and the following tests are requested and performed. The results are as follows:

APTT = 68 seconds (25-35 sec)
Factor VIII = 35% at 1:10, 67% at 1:20 and 89% at 1:40
Factor IX = 56% 78% 102
Factor XI = 66 90 110

  • Why is it important to know this sample is from a 4 month old baby?
  • Explain the results of the factor assay and possible causes?
  • In this situation, what testing should be performed?
  • Can this sample be saved?

Donna Castellone

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About the Author

Donna Castellone,  MS, MT(ASCP)SH

Donna Castellone,
MS, MT(ASCP)SH

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