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Coagulation Case Studies


Wednesday, September 3, 2008

SEPTEMBER CASE STUDY

SEPTEMBER CASE STUDY:

A known 3 year old hemophiliac patient has being admitted to a small hospital and need to be transferred to your hospital for a possible treatment. A sample is collected and rushed to the special coagulation laboratory. The APTT is run and the result is > 100 seconds. One point is run to quickly give the pediatric hematologist a result and the 1:10 dilution is 32%. This does not correspond to an APTT of > 100 seconds. The complete results are:
1:20 = 54%
1:40= 75%
1:80=98%

What is a possible explanation for this result? Should this patient receive product, based on the APTT result? What is the factor assay telling us? What test can be done to confirm this?

Donna Castellone

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About the Author

Donna Castellone,  MS, MT(ASCP)SH

Donna Castellone,
MS, MT(ASCP)SH

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