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Learning Center
Hemostasis Happenings
Wednesday, June 3, 2009
HEMOSTASIS HAPPENINGS: JUNE 2009
11th Annual Symposium on Bleeding and Thrombosis
Monday, June 15 and Tuesday, June 16, 2009
The Westin Hotel Indianapolis
50 South Capitol Avenue
Indianapolis, IN 46204
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Course Agenda - Monday, June 15, 2009
7:45 - 8:00 Welcome and Introductions
8:00 - 8:45 Thrombophilia Testing: A Necessity...
8:45 - 9:30 Thrombophilia Testing: ...Not Necessarily
9:30 - 10:00 Thrombophilia Testing: Pearls and Pitfalls
10:00 - 10:45 Networking Break and Exhibitor Showcase
10:45 - 11:30 Intriguing Case Reviews
11:30 - 12:15 Aging and Thrombosis
12:15 - 1:30 Technology Review Lunch and Exhibitor Showcase
1:30 - 2:15 The Perfect Anticoagulant
2:15 - 3:00 Antiplatelet therapy
3:00 - 3:45 Networking Break and Exhibitor Showcase
3:45 - 5:45 Coag 101: A (Re-) Introduction to Hemostasis
5:45 - 7:45 Cocktail Gala Reception and Exhibitor Showcase
Course Agenda—Tuesday, June 16, 2009
7:45 - 8:00 Welcome and Introductions
8:00 - 8:45 Antiphospholipid Antibodies: A Necessity...
8:45 - 9:30 Antiphospholipid Antibodies: ...Not Necessarily
9:30 -10:00 Antiphospholipid Antibody testing: Pearls and Pitfalls
10:00 - 10:45 Networking Break and Exhibitor Showcase
10:45 - 11:30 Platelet Function Testing
11:30 - 12:15 Throbolytic Therapy Utility for VTE
12:15 - 1:30 Technology Review Lunch and Exhibitor Showcase
1:30 - 2:15 Thrombotic Challenges to Women's Health
2:15 - 3:00 Inflammation and the Hemostatic System
INTERNATIONAL SOCIETY OF THROMBOSIS & HEMOSTASIS
THIS MEETING IS IN JULY -
BUT NOTE, THE SSC COMMITTEE MEETINGS ARE FREE- ANYONE CAN ATTEND- HERE IS THE SCHEDULE
Boston Convention & Exhibition Center415 Summer StreetBoston, Massachusetts 02210
Saturday (July 11)SSC Sessions - 08:00 AM to 12:00 AM
Hemostasis and Malignancy
Educational Session - 8:00 AM - 9:30 AM
Moderator: Martin H. Prins (The Netherlands)
Frederick R. Rickles (USA)
Coagulation as a biological target for cancer therapy
Alok A. Khorana (USA)
Predicting cancer patients at risk for venous thromboembolism: Strategies for Prophylaxis
Agnes Y. Lee (Canada)
Diagnosis and management of cancer-associated thrombosis
Business Session - 9:30 AM - 12:00 AM
Platelet Immunology
Business Session - 8:00 AM - 11:00 AM
Educational Session - 11:00 AM - 12:00 AM
Moderator: Volker Kiefel (Germany)
Theodore E. Warkentin (Canada)
Laboratory testing for heparin-induced thrombocytopenia
Richard Aster (USA)
Drug-induced immune thrombocytopenias
Predictive Variables in Cardiovascular Disease
Educational Session - 08:00 AM - 09:30 AMPredictive hemostatic variables: A user's guide to applying clinical/ laboratory predictors of venous and arterial thromboembolism in everyday clinical practice
Moderators: Gordon Lowe (UK), James Douketis (Canada)
Mark Woodward (USA)
Interpreting studies of predictor variables and clinical outcomes: what does having a risk factor really mean?
Marc A. Rodger (Canada)
Developing a clinical-laboratory prediction rule for recurrent venous thromboembolism: how do we get there?
Henri Bounameaux (Switzerland)
Interpreting clinical-laboratory prediction rules: when is a Clinical Practice Guideline ready for prime time?
Business Session - 9:30 AM - 12:00 AM
Vascular Biology
Educational Session - 08:00 AM - 09:30 AMShed proteins/receptors as clinical biomarkers of vascular disease
Moderator: Peter J. Newman (USA)
Lawrence Brass (USA)
Exploring the platelet sheddome
Michael Berndt (Ireland)
Translating the mechanism of GPVI shedding: soluble GPVI as a clinical biomarker
Simone Schoenwaelder (Australia)
Platelet aging and ectodomain shedding
Business Session - 9:30 AM - 12:00 AM
Women's Health in Thrombosis & Haemostasis
Business Session - 8:00 AM - 10:30 AM
Educational Session - 10:30 AM - 12:00 AM
Moderator: Andrea H. James (USA)
Claire S. Philipp (USA)
Identifying women with Menorrhagia for hemostatic evaluation
Benjamin Brenner (Israel)
Anticoagulation During Pregnancy/ Debate: Inherited thrombophilia and pregnancy complications - anticoagulation? (Yes)
Marc A. Rodger (Canada)
Anticoagulation During Pregnancy/ Debate: Inherited thrombophilia and pregnancy complications - anticoagulation? (No)
Saturday (July 11)Educational Sessions - 12:15 AM to 01:15 PM
Robert S. Schwartz (USA)
The Illusion of Disclosure: Conflicts of interest in clinical investigation - perspectives of a Journal Editor
Saturday (July 11)Educational Sessions - 12:15 AM to 01:45 PM
APSTH-ISTH Symposium
Moderator: Yukio Ozaki (Japan)
Pantep Angchaisuksiri (Thailand)
Coagulopathy in Malaria
Takashi Morita (Japan)
Use of Asian snake venom inhibitors in studies of blood coagulation mechanism
Geoff Isbister (Australia)
Coagulopathy induced by snake bites and its management
Toshiyuki Miyata (Japan)
Genetic disorders related to coagulopahty prevalent in the Far East
Introduction to Genomics and Molecular Epidemiology
Moderator: Willem Ouwehand (UK)
Willem Ouwehand (UK)
Introduction to Genomics and Molecular Epidemiology
In silico drug design
Moderator: Gerry AF. Nicolaes (The Netherlands)
Gerry A. F. Nicolaes (The Netherlands)
Application of in silico methods in blood coagulation research: from virtual proteins to wet protein chemistry
Bruno Villoutreix (France)
In silico screening of compound collections: methods and applications for drug discovery and chemical biology
Xavier Morelli (France)
Protein-protein complexes: druggable or undruggable targets?
Translating evidence into practice
Moderators: James Douketis (Canada), Gerhard J. Johnson (USA)
Roman Jaeschke (Canada)
Developing Clinical Practice Guidelines - GRADE system experiences
Gordon Lowe (UK)
Incorporating practice guidelines into the realm of arterial and venous thromboembolism predictors: What do we have? What is missing?
Saturday (July 11)SSC Sessions - 02:00 PM to 06:00 PM
Animal Models
Business Session - 02:00 PM - 04:30 PM
Educational Session - 04:30 PM - 06:00 PM
Moderators: Hartmut Weiler (USA), Timothy C. Nichols (USA)
Thomas G. Diacovo (USA)
Modifying murine von Willebrand factor A1 domain for in vivo assessment of human platelet therapies
Eva-Marie Muchitsch (Austria)
Key questions for animal models of hemostasis in developing new drugs and obtaining approval
Mortimer Poncz (USA)
Stressing the limits of mice models of hemophilia: when mice are not small people
Biorheology
Educational Session - 02:00 PM - 03:00 PM
Moderator: Johan W.M. Heemskerk (The Netherlands)
Gerard B Nash (UK)
Adhesion of platelets and leukocytes to the vessel wall: rheological principles and critical parameters
Johan W.M. Heemskerk (The Netherlands)
Thrombus formation and the different ways to measure this
Business Session - 03:00 PM - 06:00 PM
Factor VIII & IX
Educational Session - 02:00 PM - 03:30 PM
Moderator: Alok Srivastava (India)
Kathelijn Fischer (The Netherlands)
Management of hemophilia and assessment of outcomes
Edward G.D. Tuddenham (UK)
Factor concentrates for hemophilia - current products and newer technologies
Arun Srivastava (USA)
Gene therapy of hemophilia B: overview and new possibilities
Business Session - 03:30 PM - 06:00 PM
Fibrinogen/Factor XIII
Educational Session - 02:00 PM - 03:00 PM
Moderator: Moniek de Maat (The Netherlands)
John Weisel (USA)
Fibrin gels and bioengineering/clinical applications
Aida Inbal (Israel)
Non-coagulation activities of Factor XIII
Business Session - 03:00 PM - 06:00 PM
Lupus Anticoagulant/ Phospholipid-dependent Antibodies
Business Session - 02:00 PM - 04:30 PM
Educational Session - 04:30 PM - 06:00 PM
Moderator: Vittorio Pengo (Italy)
Thomas Ortel (USA)
Antiphospholipid antibodies: Historical background
Jacob H. Rand (USA)
Mechansims of action of antiphosopholipid antibodies
Ph.G. de Groot (The Netherlands)
Laboratory diagnosis
Vittorio Pengo (Italy)
Clinical features
Perinatal/Pediatric Hemostasis
Educational Session - 02:00 PM - 03:30 PM
Moderator: Gili Kenet (Israel)
Gili Kenet (Israel)
Developmental Hemostasis
Ulrike Nowak-Gottl (Germany)
Pediatric venous thromboembolism and thrombophilia
Paul Monagle (Australia)
Anticoagulant therapy in children
Business Session - 03:30 PM - 06:00 PM
Plasma Coagulation Inhibitors
Business Session - 02:00 PM - 04:30 PM
Educational Session - 04:30 PM - 06:00 PM
Moderator: Elaine Gray (UK)
Trevor Baglin (UK)
Antithrombin and heparin Co-factor II: Structure and function
Elisabetta Castoldi (The Netherlands)
Molecular mechanisms of thrombosis risk in protein S deficiency
Steven Kitchen (UK)
Laboratory investigation of thrombophilia
Sunday (July 12)SSC Sessions - 08:00 AM to 12:00 AM
Control of Anticoagulation
Business Session - 08:00 AM - 10:30 AM
Educational Session - 10:30 AM - 12:00 AM
Moderators: Trevor Baglin (UK), Sam Schulman (Canada)
Elaine Hylek (USA)
Atrial fibrillation and antithrombotic therapy: which drug and when?
David Keeling (UK)
Interruption of oral VKA therapy requires bridging therapy (for)
Clive Kearon (Canada)
Interruption of oral VKA therapy requires bridging therapy (against)
Brian Gage (USA)
Warfarin dosing and pharmacogenetic testing (for)
David A. Garcia (USA)
Warfarin dosing and pharmacogenetic testing (against)
DIC
Educational Session - 08:00 AM - 09:30 AM
Disease-Specific Molecular Mechanisms in Disseminated Intravascular Coagulation (DIC)
Moderator: Cheng-Hock Toh (UK)
Peter A. Ward (USA)
Role of IL-17 in Sepsis
Karim Brohi (UK)
New Concepts in Trauma Induced Coagulopathy
Katherine A. Hajjar (USA)
Acute Promyelocytic Leukemia: Mechanisms of Coagulopathy
Business Session - 09:30 AM - 12:00 AM
Fibrinolysis
Business Session - 08:00 AM - 10:30 AM
Educational Session - 10:30 AM - 12:00 AMFibrinolysis/ D-dimer
Moderator: Carl-Erik H Dempfle (Germany)
Carl-Eric Dempfle (Germany)
D-dimer in the emergency room (venous thromboembolism exclusion, aortic dissection)
Wolfgang Korte (Switzerland)
Fibrin generation markers in the perioperative setting
Saskia Middledorp (The Netherlands)
D-dimer as prognostic parameter in venous thromboembolism, pregnancy and cancer
Plasma Kallikrein-Kinin System
Business Session - 08:00 AM - 11:00 AM
Educational Session - 11:00 AM - 12:00 AMActivation of the Plasma Contact System In Vivo
Moderator: David Gailani (USA)
Martijn Gebbink (The Netherlands)
Misfolded proteins as a trigger for contact activation
Thomas Renne (Sweden)
Role of leukocytes and platelets in contact system activation
Platelet Physiology
Business Session - 08:00 AM - 11:00 AM
Educational Session - 11:00 AM - 12:00 AM
Moderator: Marco Cattaneo (Italy)
Alan D. Michelson (USA)
Platelet function as a Guide to Thrombotic Risk
Catherine P.M. Hayward (Canada)
Recent advances in the understanding and diagnosis of inherited platelet function disorders
Registry of Exogenous Hemostatic Factors
Business Session - 08:00 AM - 10:30 AM
Educational Session - 10:30 AM - 12:00 AMExogenous Hemostatic Factors
Moderator: Mary Ann McLane (USA)
Ivo Francischetti (USA)
Transcriptomics and functional genomics of salivary glands from hematophagous arthropods
Francis S. Markland (USA)
Fibrolase and its evolution to clinical trials: a long and winding road
Von Willebrand Disease
Educational Session - 08:00 AM - 09:30 AMVon Willebrand Disease (VWD) Diagnosis
Moderator: David Lillicrap (Canada)
Francesco Rodeghiero (Italy)
Clinical aspects of VWD diagnosis
Robert R Montgomery (USA)
Laboratory testing of the hemostasis phenotype in VWD
Anne Goodeve (UK)
Genetic analysis as an aid in VWD diagnosis
Business Session - 09:30 AM - 12:00 AM
Sunday (July 12)Working Group on Coagulation Standards - 12:30 AM to 02:30 PM
Donna Castellone
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About the Author
Donna Castellone,
MS, MT(ASCP)SH
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