They are extracted from non-activated citrated human plasma, which is only used for these preparations. Proteins are purified with non-denaturing methods, which keep the structure and the biological activity of the native molecule. Usually proteins are lyophilized in presence of glycine, hepes and sodium chloride. Some preparations are lyophilized with excipients, which do not contain amino groups. This allows using directly the reconstituted products for covalent coupling.
Each protein is packaged with its specification sheet, which includes an analysis certificate, indicating the protein content (Lowry method and absorbance at 280 nm) and the specific activity.
The protein content in each vial is expressed by weight (ìg or mg) and, when required, by its biological content, indicated in Plasma Equivalent Units (PEU) or units (U). One PEU or U is the amount in 1 mL of normal human plasma.
Viral safety: The material used for protein preparation is tested with registered methods and found negative for HIV (1 and 2) antibodies, HBs Ag and HVC antibodies. However, no assay may warrant the total absence of infectious agents. Any product of human origin must then be handled with all the required cautions, as being potentially infectious.
|APP004L||Anti-Thrombin (AT) (10 x 1.5 mg)||$1,656.00|
|APP004A||Anti-Thrombin (AT) (1 x 150 µg)||$115.00|
|APP004B||Anti-Thrombin (AT) (1 x 1.5 mg)||$220.00|
|APP004K||Anti-Thrombin (AT) (6 x 150 µg)||$308.00|
|APP004D||Anti-Thrombin (AT) (1 x 3.75 mg)||$385.00|
|APP004C||Anti-Thrombin (AT) (1 x 10 mg)||$681.00|
|APP010A||Purified B2-Glyco-Protein I (B2GP1)||$368.00|
|APP020A||Fibrin Fragment E (FFE)||$107.00|
|APP016A||Fibrinogen Fragment D||$94.00|
|APP017A||Fibrinogen Fragment DD||$94.00|
|APP018A||Fibrinogen Fragment E||$94.00|
|APP019A||Fibrinogen Fragment E3t||$107.00|
|APP001C||Purified Human Fibrinogen (1 x 1 g)||$592.00|
|APP001K||Purified Human Fibrinogen (6 x 5 mg)||$157.00|
|APP001A||Purified Human Fibrinogen (1 x 5 mg)||$40.00|
|APP001B||Purified Human Fibrinogen (1 x 100 mg)||$188.00|
|APP002C||Purified Human Fibrinogen, Plasminogen Free (1 x 1 g)||$615.00|
|APP002A||Purified Human Fibrinogen, Plasminogen Free (1 x 5 mg)||$51.00|
|APP002K||Purified Human Fibrinogen, Plasminogen Free (6 x 5 mg)||$188.00|