Chromogenic assays

BIOPHEN Plasminogen (CE Marked)
For Research Use Only in the United States and Canada

Clotting, Deficient Plasmas, & Chromogenic Assays products are available worldwide

Chromogenic assay of plasminogen tested as a plasminogen streptokinase complex, by its specific activity on a chromogenic substrate. Insensitive to the fibrinogen concentration.

Assay characteristics

Kit components

Applications

Total Assay Time:

Detection Threshold:                                                ≤ 10%

Dynamic Range:                                                  10-150%

Intra-Assay CV:                                                        < 4%

Inter-Assay CV:                                                        < 6%

No significant interference observed for heparin concentrations <2 IU/mL, Bilirubin concentrations <0.2 mg/mL, and hemoglobin concentrations <2 mg/mL in plasma.

No significant interference of plasma fibrinogen concentration in the assay.

R1: 2x2.5 mL Activation reagent containing streptokinase (about 25,000 IU) and plasminogen-free fibrinogen

R2: 2x6.25 mg of Chromogenic substrate, specific for Plasmin and “plasminogen-streptokinase” complexes (SPm41).

Assay of Plasminogen in human plasma for the diagnosis of hereditary or acquired Plasminogen deficiencies.

Assay of plasminogen in any biological fluid where it must be measured.