Medicago AB Products Are Available Worldwide

For Research Use Only

Artocarpus integrifolia lectin (Jacalin), isolated by affinity chromatography from jackfruit seeds, belongs to the family of galactose-binding lectins. Jacalin is a tetrameric two-chain lectin with a molecular weight of 66 kDa. Applications include isolating IgA from human serum, isolating human plasma glycoproteins and histochemistry.

A post-translational proteolytic modification of Jacalin gives the lectin a novel carbohydrate-binding site involving the N terminus of the α-chain. The relative affinities of the lectin for galactose derivatives, as well as the structural basis of its T-antigen specificity, are explained by its protein structure.

Jacalin is supplied without preservatives as a lyophilized white to light-yellow powder, essentially salt-free.

For laboratory use only.