BIOPHEN™ AT Anti-IIa — antitrombiini aktiivsuse määramine Anti-IIa kromogeense analüüsiga
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BIOPHEN™ AT Anti-IIa — antitrombiini aktiivsuse määramine Anti-IIa kromogeense analüüsiga

Code: A221122-RUO
Manufacturer’s Part Number: 221122-RUO
Toote maht: 2 × 2,5 ml
Kõrvaldamine: RUO

Price: $112.00

Kogus

Toote kirjeldus

Ainult teadustööks. Ei tohi kasutada diagnostilistes protseduurides.

Chromogenic anti-IIa assay for antithrombin (AT) activity in human citrated plasma or purified milieu. Uses bovine Factor IIa in the presence of excess heparin. CE-IVD.

The anti-IIa method measures AT's ability to inhibit thrombin, providing complementary information to anti-Xa methods. Particularly important for detecting Type II HBS (Heparin Binding Site) AT deficiency, where anti-Xa activity may appear normal but anti-IIa is reduced. Using both methods together enables complete AT deficiency subtype classification.

  • Anti-IIa method — detects AT subtypes missed by anti-Xa assays alone
  • Uses bovine Factor IIa — complementary to human Xa-based BIOPHEN™ AT assays
  • For complete AT Type I / Type II subtype characterization
  • CE-IVD

Toote omadused

  • Analüüsi koguaeg: < 3 min
  • Detection Threshold: ≤ 15%
  • Dünaamiline ulatus: 0–100%
  • Analüüsi sisene variatsioonikoefitsient (CV): < 3%
  • Inter-Assay CV: ≤ 5%
  • Hepariini kofaktori II, α2-makroglobuliini ega α1-antitrüpsiini mõju puudub.

Toote komponendid

  • R1: 2 x 2.5 mL Bovine Thrombin, lyophilized.
  • R2: 2 x 2.5 mL Chromogenic substrate specific for Thrombin, lyophilized.
  • R3: 2 x 25 mL Sample Diluent with heparin, ready to use.

Toote kasutusvaldkonnad

Measurement of antithrombin (AT) activity in research applications.

Saadaval on vastavad kalibraatorid ja kontrollproovid: BIOPHEN™ plasma kalibraator (viitenumber A222101-RUO), BIOPHEN™ normaalne kontrollplasma (viitenumber A223201-RUO) ja BIOPHEN™ ebanormaalne kontrollplasma (viitenumber A223301-RUO).