BIOPHEN™ AT Anti-IIa — Antitrombinaktivitet Anti-IIa kromogen analyse
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BIOPHEN™ AT Anti-IIa — Antitrombinaktivitet Anti-IIa kromogen analyse

Code: A221122-CAN
Manufacturer’s Part Number: 221122
Produktstørrelse: 2 x 2,5 ml
Klaring: CE / HCL

Price: $112.00

Antall

Produktbeskrivelse

Chromogenic anti-IIa assay for antithrombin (AT) activity in human citrated plasma or purified milieu. Uses bovine Factor IIa in the presence of excess heparin. CE-IVD.

The anti-IIa method measures AT's ability to inhibit thrombin, providing complementary information to anti-Xa methods. Particularly important for detecting Type II HBS (Heparin Binding Site) AT deficiency, where anti-Xa activity may appear normal but anti-IIa is reduced. Using both methods together enables complete AT deficiency subtype classification.

  • Anti-IIa method — detects AT subtypes missed by anti-Xa assays alone
  • Uses bovine Factor IIa — complementary to human Xa-based BIOPHEN™ AT assays
  • For complete AT Type I / Type II subtype characterization
  • CE-IVD

Produktegenskaper

  • Total analysetid: < 3 min
  • Detection Threshold: ≤ 15%
  • Dynamisk område: 0 til 100 %
  • Intra-assay CV: < 3 %
  • Inter-Assay CV: ≤ 5%
  • Ingen interferens fra heparin-kofaktor II, α2-makroglobulin eller α1-antitrypsin.

Produktkomponenter

  • R1: 2 x 2.5 mL Bovine Thrombin, lyophilized.
  • R2: 2 x 2.5 mL Chromogenic substrate specific for Thrombin, lyophilized.
  • R3: 2 x 25 mL Sample Diluent with heparin, ready to use.

Produktapplikasjoner

Measurement of antithrombin (AT) activity in research applications.

Associated calibrator and controls are available: BIOPHEN™ Plasma Calibrator (Ref A222101-CAN), BIOPHEN™ Normal Control Plasma (Ref A223201-CAN) and BIOPHEN™ Abnormal Control Plasma (Ref A223301-CAN).

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