Nitrochinolino-N-oksidas – teigiamieji kontroliniai mėginiai Ames MPF, umuC (20 mikrogramų)

4-Nitroquinoline-N-oxide (4-NQO) positive control mutagen for Ames MPF and umuC assays. 20 µg. Direct-acting UV-mimetic mutagen. No S9 required. Research use only.

4-NQO is a UV-mimetic direct-acting mutagen that induces oxidative DNA damage causing base-pair substitutions. It is the reference direct-acting positive control for TA100 and TA1535 base-pair substitution strains and for the umuC SOS assay. Also relevant in photogenotoxicity research for its UV-mimetic oxidative damage mechanism.

• Base-pair substitution mutagen — TA100 and TA1535 specific
• UV-mimetic oxidative DNA damage mechanism
• Tiesioginio veikimo — S9 nereikalingas
• 20 µg research control quantity