Tetracycline for Ames Test Strain Verification

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Tetracycline solution for Ames mutagenicity assay tester strain genetic marker verification per OECD TG 471. Before use, Ames tester strains must be verified for their required genetic characteristics — including antibiotic resistance markers that confirm plasmid integrity.

Certain Ames tester strains carry tetracycline resistance markers: TA102 carries the pAQ1 plasmid (tetracycline resistance), and TA97a also carries tetracycline resistance markers. Growth on tetracycline-supplemented plates confirms these strains retain their required plasmid(s) and have not lost genetic markers during culture and storage.

• For Ames tester strain genetic marker verification (OECD TG 471)
• Confirms tetracycline resistance in TA102 (pAQ1 plasmid) and TA97a
• Verifies strain identity and plasmid integrity prior to mutagenicity testing