PB/β-Naphtoflavone-Induced Hamster Liver S9 Fraction — 1 mL Liquid

Только для научных исследований. Не предназначено для использования в диагностических процедурах.

PB/β-Naphtoflavone (phenobarbital/β-naphtoflavone)-induced Hamster Liver S9 fraction, liquid format. 1 mL. Post-mitochondrial supernatant pooled from Golden Syrian Hamster livers with broad cytochrome P450 enzyme coverage via dual PB/β-NF co-induction.

Hamster liver S9 has a distinct cytochrome P450 enzyme profile compared to rat S9, particularly relevant for compounds that undergo species-specific bioactivation. Hamster S9 is used preferentially in the Enhanced Ames Test (OECD 471) for nitrosamines and in ADME pharmacokinetic studies for pharmaceutical preparations where hamster metabolic activation is required.

• For Ames MPF, Ames II, umuC, and micronucleus genotoxicity assays
• Complementary metabolic profile to standard rat S9
• Preferred for nitrosamines per OECD 471
• Liquid format — no reconstitution required. 1 mL.