For Research Use Only. Not for Use in Diagnostic Procedures.

Rapid Micronucleus MoA (Mode of Action) Centromere Telomere is a ready-to-use kit for fast identification of chromosomal breakage (clastogenic effect) or damage to the spindle apparatus (aneugenic effect) in dividing mammalian cells — including primary human lymphocytes and the TK6 cell line. 100-slide format for medium-to-high throughput mechanistic genotoxicity studies.

Uses simultaneous centromere and telomere FISH with PNA probes on binucleated cells to distinguish aneugenic (centromere-positive MN) from clastogenic (centromere-negative MN) mechanisms. Also detects NPBs and NBUDs. Compliant with OECD TG 473 and OECD TG 487. 100-slide format for regulatory genotoxicity programs requiring full MoA characterization.