Xenometrix bioassay systems for environmental water quality monitoring — covering genotoxicity and endocrine disruption endpoints required by international water quality regulations and OECD testing frameworks. Two primary assay systems are validated for water testing applications.
The umuC SOS induction assay is standardized under ISO 13829 (Determination of genotoxicity of water and waste water using the umu-test) and is widely used for monitoring surface water, drinking water, wastewater effluents, and sediment extracts for genotoxic contamination — providing a rapid, cost-effective bacterial bioassay ahead of more resource-intensive Ames test confirmation.
The XenoScreen YES (Yeast Estrogen Screen, ISO 19040-1) and XenoScreen YAS (Yeast Androgen Screen) provide quantitative estrogenic and androgenic activity measurement for monitoring endocrine disruptors in water matrices — expressing results as estradiol equivalents (EEQ) and dihydrotestosterone equivalents (DHTEQ) from standard curves. These assays are accepted by regulatory agencies for endocrine disruption screening under the EU Water Framework Directive, REACH, and OECD Conceptual Framework for endocrine disruptor testing.
All Xenometrix water testing bioassay kits include complete validated protocols, positive and negative controls, and reference compound standard curves designed to meet ISO acceptance criteria.