BIOPHEN™ chromogenic assays and substrate plasmas from HYPHEN BioMed for hemophilia A and B diagnosis, inhibitor testing, and factor concentrate monitoring.

BIOPHEN™ FVIII:C uses human Factor IX and Factor X reagents validated for emicizumab (Hemlibra®) FVIII-like activity measurement — the method recommended by international guidelines for FVIII monitoring in patients receiving emicizumab prophylaxis. BIOPHEN™ FVIII Variant uses bovine Factor X and is specifically insensitive to emicizumab, enabling accurate measurement of endogenous or infused FVIII separately from emicizumab activity.

BIOPHEN™ Factor IX chromogenic assay is traceable to the WHO international FIX standard and validated for monitoring extended half-life FIX products including Alprolix®, Idelvion®, and Rebinyn®. FVIII inhibitor plasmas at mild, moderate, and severe levels validate Bethesda and Nijmegen-modified Bethesda assay performance.


Reference Product Name Price
CE  /  HCL
A221402-CAN
BIOPHEN™ FVIII:C Chromogenic Assay (2 × 2.5 mL) $525.00
RUO
A221402-RUO
BIOPHEN™ FVIII:C Chromogenic Assay (2 × 2.5 mL) $549.00
CE  /  HCL
A221406-CAN
BIOPHEN™ FVIII:C Chromogenic Assay (2 × 6 mL) $924.00
RUO
A221406-RUO
BIOPHEN™ FVIII:C Chromogenic Assay (2 × 6 mL) $965.00
CE  /  HCL
ADP040A-CAN
FVIII:C Deficient Plasma (1 × 1 mL) — <1% Residual Discontinued
RUO
ADP040A-RUO
FVIII:C Deficient Plasma (1 × 1 mL) — <1% Residual Price Inquiry
CE  /  HCL
ADP040K-CAN
FVIII:C Deficient Plasma (6 × 1 mL) — <1% Residual $368.00
RUO
ADP040K-RUO
FVIII:C Deficient Plasma (6 × 1 mL) — <1% Residual $385.00
RUO
ARK039A-RUO-MIN
ZYMUTEST™ Anti-FVIII IgG MonoStrip — FVIII Inhibitor ELISA $768.00
CE  /  HCL
A221802-CAN
BIOPHEN™ Factor IX Chromogenic Assay (2 × 2.5 mL) $567.00
RUO
A221802-RUO
BIOPHEN™ Factor IX Chromogenic Assay (2 × 2.5 mL) $593.00
CE  /  HCL
A221806-CAN
BIOPHEN™ Factor IX Chromogenic Assay (2 × 6 mL) $987.00
RUO
A221806-RUO
BIOPHEN™ Factor IX Chromogenic Assay (2 × 6 mL) $1,032.00
RUO
ADP050A-RUO
Factor IX Deficient Plasma (1 × 1 mL) — <1% Residual Discontinued
RUO
ADP050K-RUO
Factor IX Deficient Plasma (6 × 1 mL) — <1% Residual $385.00
RUO
ARK032A
ZYMUTEST™ Factor IX — FIX Antigen ELISA $768.00
RUO
A221801-RUO
BIOPHEN™ Factor IX Chromogenic Assay (2 × 1 mL) $411.00
CE  /  HCL
A221801-CAN
BIOPHEN™ Factor IX Chromogenic Assay (2 × 1 mL) $394.00
CE  /  HCL
ADP050K-CAN
Factor IX Deficient Plasma (6 × 1 mL) — <1% Residual $368.00