PB/β-Naphthoflavone-Induced Hamster Liver S9 Fraction — 5 mL Liquid
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PB/β-Naphthoflavone-Induced Hamster Liver S9 Fraction — 5 mL Liquid

Code: APRS-H-PB05LIQ
Manufacturer’s Part Number: PRS-H-PB05LIQ
Product size: 5 ml, frozen liquid
Clearance: RUO

Price: $378.00

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Product Description

For Research Use Only. Not for Use in Diagnostic Procedures.

PB/β-Naphthoflavone (phenobarbital/β-naphthoflavone)-induced Hamster Liver S9 fraction, liquid format. 5 mL bulk format. Post-mitochondrial supernatant pooled from Golden Syrian Hamster livers for extended or high-volume genotoxicity testing programs.

Hamster liver S9 is used preferentially in the Enhanced Ames Test (OECD 471) for nitrosamines, and in ADME pharmacokinetic studies. The distinct cytochrome P450 enzyme profile of hamster S9 enables detection of compounds preferentially bioactivated via hamster-specific metabolic pathways — complementing standard rat S9 for comprehensive species-specific mutagenicity screening.

  • For Ames MPF, Ames II, umuC, and micronucleus genotoxicity assays
  • Complementary CYP450 profile to rat S9
  • Preferred for nitrosamines per OECD 471
  • Liquid format — no reconstitution. 5 mL bulk format.

Product Characteristics

  • Protein Concentration: 25 - 35 mg/ml
  • High activities of Cytochrome P450: 1A2 (MROD), 1A1, 1A2 (EROD), 3A, 2B (BROD), 2B1, 2B2 (PROD)
  • Storage: -20 or -80 oC
  • Shipment on dry ice from storage in Germany or from Switzerland
  • Shelf Life: 12 -24 months
  • In full compliance with OECD 471 guideline, ICH M7
  • Requested volumes in different Ames test: 0.44 mL/strain/compound in MicroAmes24, 0.35 mL/strain/ compound in Ames MPF, 1.4 mL / strain/ compound in Ames agar plate Test

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Product Applications

Instructions For Use

Data Sheet/Technical Data

Certificate of Analysis (COA)

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