Ames — Semisolid S. typhimurium Strain YG1041
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Ames — Semisolid S. typhimurium Strain YG1041

Code: APSS-0121
Manufacturer’s Part Number: PSS-0121
Product size: 250 µl after Reconstitution
Clearance: RUO

Price: $157.00

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Product Description

For Research Use Only. Not for Use in Diagnostic Procedures.

Salmonella typhimurium YG1041 tester strain, semisolid format. 250 µL. Store at −70°C.

YG1041 is a TA98 derivative engineered to overexpress nitroreductase (nfsI) and O-acetyltransferase (oat) enzymes, dramatically increasing sensitivity to:

  • Nitroarenes (e.g., 1-nitropyrene, 2-nitrofluorene) — activated by overexpressed nitroreductase
  • Aromatic and heterocyclic amines (e.g., 2-aminofluorene, heterocyclic food mutagens) — activated by overexpressed O-acetyltransferase

YG1041 detects these compounds via frameshift mutations (TA98 base), and is used alongside YG7108 (the isogenic nitroreductase/OAT-deleted control) to confirm mechanism of action. For environmental carcinogen research, food safety, and pharmaceutical impurity screening. OECD TG 471 compatible.

Product Characteristics

  • Mutation: hisD3052
  • Type: Frameshifts
  • Target: GCGCGCGC
  • rfa Mutation: defective lipopolysaccharide (LPS) layer
  • uvrB Mutation: Eliminates the accurate excision repair mechanism
  • pKM101 R-Factor Plasmid: Enhances chemical and UV-induced mutagenesis, Ampicillin Resistance
  • Plasmid pYG233 includes genes encoding the two enzymes nitroreductase and acetyltransferase. The plasmid also confers resistance to kanamycin.
  • Strains are validated for shipment at room temperature from warehouse in Germany or in Switzerland

Product Components

Product Applications

Material Safety Data Sheet (MSDS)

Data Sheet/Technical Data

Certificate of Analysis (COA)

Other Documents