Artocarpus integrifolia lectin (Jacalin) (10 mg)
For Research Use Only
Jacalin, isolated by affinity chromatography from jackfruit seeds, belongs to the family of galactose-binding lectins. Jacalin is a tetrameric two-chain lectin with a molecular weight of 66 kDa. Applications include isolating IgA from human serum, isolating human plasma glycoproteins and histochemistry.
A post-translational proteolytic modification of Jacalin gives the lectin a novel carbohydrate-binding site involving the N terminus of the α-chain. The relative affinities of the lectin for galactose derivatives, as well as the structural basis of its T-antigen specificity, are explained by its protein structure.
Artocarpus integrifolia lectin is supplied without preservatives as a lyophilized white to light-yellow powder, essentially salt-free.For laboratory use only.
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Highly specific for the tumour-associated T-antigenic disaccharide.
Agglutinates human erythrocytes at a concentration of ≥7.8 µg/ml.
|Appearance: White to light-yellow lyophilized powder. |
Source: Jackfruit seeds.
Activity: Agglutinates human erythrocytes at a concentration of ≥ 7,8 µg/ml. Blood group non-specific after neuraminidase treatment.
Microorganisms: < 100 CFU/g.
Protein: > 80%.
Identity: SDS-PAGE, two homogeneous bands at 12 kDa and 16 kDa.
Shelf life: > Five years when stored at -20°.
|Isolation of IgA from human serum. |
Isolation of human plasma glycoproteins.
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|Artocarpus integrifolia lectin||Artocarpus integrifolia lectin||N/A||N/A|