2-Aminofluorene - Positive Controls for Ames MPF, Ames II, umuC
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2-Aminofluorene - Positive Controls for Ames MPF, Ames II, umuC

Code: APPC-AF10
Manufacturer’s Part Number: PPC-AF10
Product size: 1 x 10 mg
Clearance: RUO

Price: $141.00

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Product Description

2-Aminofluorene (2-AF) positive control mutagen for Ames MPF, Ames II, and umuC assays. 10 mg. S9-dependent aromatic amine. Research use only.

2-Aminofluorene requires S9 metabolic activation to the mutagenic N-hydroxy form. It induces both frameshift mutations (detected by TA98) and base-pair substitutions (detected by TA100), making it a dual-activity S9-dependent positive control that simultaneously validates S9 function across the two most important OECD 471 tester strains.

  • Dual-activity: frameshift (TA98) + base-pair substitution (TA100)
  • S9-dependent — validates metabolic activation across two strains simultaneously
  • 10 mg — extended supply for multi-study programs

Product Characteristics

  • 2-Aminofluorene (AF10) for use as an alternative positive control in Ames mutagenicity tests that use E.coli strains in the presence of S9. It can be used instead of 2-Aminoanthracene.

Product Components

  • Suitable for use with Ames MPF PENTA I, C10-512.
  • 1 x 10 mg.

Product Applications

Instructions For Use

Material Safety Data Sheet (MSDS)

Data Sheet/Technical Data

Certificate of Analysis (COA)

Other Documents