The use of DOAC’s are becoming more and more popular for patients with AF and those at risk for clots. Having reversal agents for both direct thrombin inhibitors and Xa inhibitors have increased their safety and made their appeal for use widespread.
Coagulation is a complex process involving platelets, coagulation factors and the fibrinolytic system. Patient conditions or environmental factors may also impact bleeding and clotting formation. What happens to coagulation intraoperatively and postoperatively?