Product Spotlight:
PB/β-Napthtoflavone-Induced Hamster Liver S9 Fraction
APRS-H-PB01LIQ and APRS-H-PB05LIQ
For Research use Only. Not for Use in Diagnostic Procedures.
Background:
- Hamster S9 is essential for the Enhanced Ames Test (EAT), used to detect nitrosamines and genotoxic impurities in pharmaceuticals and packaging materials for pharmaceuticals and food.
- Regulatory authorities recommend the Enhanced Ames Test (EAT) for these applications.
- Because bacteria cannot metabolize certain molecules, mutagenic potential is assessed both directly and with metabolic activation (using microsomal fraction S9 from rat or hamster).
- Price of PB/NF-induced S9 cannot be compared to uninduced S9 due to differences in metabolic activity and regulatory requirements for treated animals.
- The S9 Cofactor Solution Kit for preparing the S9 Mix is available separately to allow flexibility
- High CYP Conversion Rate
- Protein Concentration: 30 mg/mL
- Exceptional Quality
- Frozen Preparation: Available in 1 mL or 5 mL formats
- Quality Control: Tested in various Ames Test formats : Petri Dish Assay, liquid microplate fluctuation test, 6-well agar plate test
- S9 Cofactor Solution Kits: Available for all S9 products