The Ames MPF and Ames II assays are modified versions of the Ames test using liquid culture instead of agar plates. The assays are based on the fluctuation method cited in OECD Guidline 471 but use 384-well microtiter plates and have a colorimetric read-out. The great advantage of this format is the lower amount of sample needed and much easier handling. The Ames MPF assays use TA98 and/or TA100, TA1535, TA1537. All these test strains are recommended in the current, formal test guidelines.

The Ames II assay differs from the Ames MPF assays in that it comprises TA98 and TAMix, consisting of 6 histidine mutant Salmonella tester strains, TA7001-TA7006. Each of these mutants can be reverted only by a specific transition or transversion, so that all possible base-pair changes can be detected by TAMix. The TA700x tester strains are not included among the recommended tester strains in the current, formal test guidelines.

Xenometrix offers practical training and in-house testing of the Ames MPF and Ames II assays in its facilities in Allschwil.



Reference Product Name Price
RUO
PPC-AA02
Aminoanthracene - Positive Controls for Ames MPF (umuC) (2 mg) $135.00
RUO
PPC-AC02
N4-Aminocytidine - Positive Control $134.00
RUO
PPC-AF10
2-Aminofluorene - Positive Control $163.00
RUO
PPC-AR05
Aminoacridine - Positive Controls for Ames MPF (umuC) (1000 µg) $62.00
RUO
PPC-NF00
Nitrofluorene - Positive Controls for Ames MPF (umuC) (20 µg) $76.00
RUO
PPC-NQ02
Nitroquinoline-N-oxide - Positive Controls for Ames MPF (umuC) (20 µg) $87.00
RUO
PRS-AC00
Ames Rat Liver S9 (Lyophilized) (1254 Aroclor) (0.4 mL) $75.00
RUO
PRS-AC01
Ames Rat Liver S9 (Lyophilized) (1254 Aroclor) (1 mL) $110.00
RUO
PRS-AC02
Ames Rat Liver S9 (Lyophilized) (1254 Aroclor) (2 mL) $141.00
RUO
PRS-PB00
Ames Rat Liver S9 (Lyophilized) (PB/BN Induced) (0.4 mL) $83.00
RUO
PRS-PB01
Ames Rat Liver S9 (Lyophilized) (PB/BN Induced) (1 mL) $116.00
RUO
PRS-PB02
Ames Rat Liver S9 (Lyophilized) (PB/BN Induced) (2 mL) $151.00
RUO
PSS-0110
Ames-Semisolid S. Typhimurium Strains (TA98) $159.00
RUO
PSS-0111
Ames-Semisolid S. Typhimurium Strains (TA100) $159.00
RUO
PSS-0112
Ames-Semisolid S. Typhimurium Strains (TA1535) $159.00
RUO
PSS-0113
Ames-Semisolid S. Typhimurium Strains (TA1537) $159.00
RUO
PSS-0115
Ames-Semisolid E. coli Strains (E. coli UvrA) $159.00
RUO
PSS-0116
Ames-Semisolid E. coli Strains (E. coli pKM101) $159.00
RUO
PSS-0119
Ames-Semisolid E. coli Strains (E. coli WP2 UvrA) $159.00
RUO
B10-513
Ames MPF Penta 2 - 10 Sample Kit $6,336.00