The Ames MPF and Ames II assays are modified versions of the Ames test using liquid culture instead of agar plates. The assays are based on the fluctuation method cited in OECD Guidline 471 but use 384-well microtiter plates and have a colorimetric read-out. The great advantage of this format is the lower amount of sample needed and much easier handling. The Ames MPF assays use TA98 and/or TA100, TA1535, TA1537. All these test strains are recommended in the current, formal test guidelines.

The Ames II assay differs from the Ames MPF assays in that it comprises TA98 and TAMix, consisting of 6 histidine mutant Salmonella tester strains, TA7001-TA7006. Each of these mutants can be reverted only by a specific transition or transversion, so that all possible base-pair changes can be detected by TAMix. The TA700x tester strains are not included among the recommended tester strains in the current, formal test guidelines.

Xenometrix offers practical training and in-house testing of the Ames MPF and Ames II assays in its facilities in Allschwil.



Reference Product Name Price
RUO
APCO-1800
S9 Cofactor Kit for Metabolic Activation in Ames Test, Micronucleus Test - 70 mL $348.00
RUO
APRS-H-PB01LIQ
PB/ß-Naphtoflavone induced Hamster Liver S9 Fraction for Enhanced Ames Test $127.00
RUO
APRS-H-PB05LIQ
PB/ß-Naphtoflavone induced Hamster Liver S9 Fraction for Enhanced Ames Test $378.00
RUO
APSS-0118
Ames – Semisolid S. typhimurium Strain TA1535pSK1002 for UmuC $201.00
RUO
APSS-0121
Ames – Semisolid S. typhimurium Strain YG1041 $157.00
RUO
APSS-0122
Ames – Semisolid S. typhimurium Strain YG1042 Price Inquiry
RUO
APSS-0123
Ames – Semisold S. typhimurium Strain YG7108 $157.00
RUO
AUMU-TGM
TG Medium for UmuC Genotoxicity Test $101.00
RUO
AW02-210-S2-P
Kit for Ames Test in Petri Dishes OECD TG471 – MacroAmes1 98/100 without Glucose Plates $1,118.00
RUO
AX02-514-S2-P
Kit for Ames Test in Petri Dishes OECD TG471 - MacroAmes1 Penta 3 without Glucose Plates $1,794.00
RUO
APRS-H-PB03LIQ
PB/ß-Naphtoflavone-induced Hamster Liver S9 Fraction for Enhanced Ames Test $295.00
RUO
APTM-0001
Tetracycline for Ames Test $101.00
RUO
AS02-390-MG
Minimal Glucose Plate Reagents $884.00
RUO
AY02-514-S2-p
MicroAmes6 Penta 4 - 5 Strain Kit in 6 Well Plates $2,496.00
RUO
APLI-0114
Ames - Liquid S. typhimurium Strain, TAMix $176.00
RUO
APPC-IC01
IRC191 - Positive Control for Ames MPF, Ames II $111.00